MRCs PinPrick stimulators are used for quantitative
sensoric testing (QST) of pain and perception thresholds.
They allow a reproducible measurement and documentation of
nociceptor activation of the skin. Thus, they enable a
better diagnostic of symptoms of neuropathologic pain and
the investigation of mechanisms that
are connected with chronic pain.
The tactile stimulators have been developed and introduced
by Prof. Rolf-Detlef Treede and PD Dr. Walter Magerl
(Department of Neurophysiology, Medical Faculty Mannheim,
University of Heidelberg). They
are used by the members of the
German Research Network on Neurophathic Pain (DFNS) and validated by the European
Federation of Neurological Societies.
The PinPrick-Sets are directly available from
information or to get a quotation please give us a call or write an email.
Pinprick stimulation ...
- is used to assess gain and loss of mechanical sensory functions
- is one important contribution to characterize the somatosensory phenotype of patients with neuropathic pain
- provides quantitative data for mechanical detection and pain thresholds as well as stimulus/response functions
- provides quantitative data for pain summation to repetitive stimuli
- is an important step towards mechanism based treatment of pain syndromes
- is a reproducible method to diagnose changes of pain sensitivity like mechanical hyperalgesia or dynamic mechanical allodynia
- is used to investigate the central sensitization to A-fibre nociceptor input
- enables the validation of paint treatment concepts by standardized protocols and absolute reference values
- Fast and safe application in clinical routine
- Approved tip geometry
- Calibrated forces
- User-independent sensoric stimulation levels
- No damage to skin tissue
- Age- and gender-matched reference values are availabe
- Recommended by German Research Network of Neuropathic Pain (DFNS)
- Recommended by European Federation of Neurological Societies
- Compact and robust design
- Patented technology
- Applicable during MRI, fMRI, and PET imaging
- One set includes seven weighted pinprick stimulators for different
pressures (between 8 and 512 mN)
- Tips have a flat contact area of 0.25 mm in diameter
with a controlled edge curvature
Accessory: Disinfection unit
For easy and safe disinfection of the PinPrick stimulators we
offer the disinfection unit as accessory.
The glass jar can
be filled with a standard disinfectant for medical
products. The PinPrick holder ensures dipping the pins into the disinfectant.
- T. Klein, W. Magerl, A. Hanschmann, M. Althaus, R.-D. Treede: Antihyperalgesic and analgesic
properties of the N-methyl-D-aspartate (NMDA) receptor antagonist neramexane
in a human surrogate model of neurogenic hyperalgesia.
European Journal of Pain, 12 (2008), 17-19 (Weblink)
- R. Rolke, W. Magerl, K.A. Campbell, C. Schalber, S. Caspari,
F. Birklein F, R.-D. Treede: Quantitative sensory testing: a
comprehensive protocol for clinical trials. Eur J Pain 10(1)
(2006), 77-88 (Weblink)
- R. Rolke, R. Baron, C. Maier, T.R. Tölle, R.-D. Treede, A. Beyer,
A. Binder, N. Birbaumer, F. Birklein, I.C. Bötefür, S. Braune, H. Flor,
V. Huge, R. Klug, G.B. Landwehrmeyer, W. Magerl, C.
Maihöfner, C. Rolko, C. Schaub, A. Scherens, T. Sprenger, M. Valet, B. Wasserka:
Quantitative sensory testing in the German Research Network
on Neuropathic Pain (DFNS): Standardized protocol and
reference values. Pain 123 (2006), 231-243 (Weblink)
- W. Magerl, P. N. Fuchs, R. A. Mayer, R.-D. Treede: Roles
of capsaicin-insensitive nociceptors in pain and secondary
hyperalgesia. Brain 124 (2001), 257-268 (Weblink)
- E. A. Ziegler, W. Magerl, R. A. Meyer, R.-D. Treede:
Secondary hyperalgesia to punctate mechanical stimuli. Brain
122 (1999), 2245-2257
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Work in progress. Subject to change without prior notice.